Candidate cytomegalovirus strain for human vaccination.


A strain of human cytomegalovirus called Towne was isolated in WI-38 human fibrolast cell cultures from the urine of an infected infant. It was then passaged 125 times in WI-38, including three clonings, and a pool was prepared in the same cell substrate for use as a potential live attenuated vaccine. The Towne virus has a broad antigenicity and cross… (More)


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@article{Plotkin1975CandidateCS, title={Candidate cytomegalovirus strain for human vaccination.}, author={Stanley A. Plotkin and T. Furukawa and N. Zygraich and C A Huygelen}, journal={Infection and immunity}, year={1975}, volume={12 3}, pages={521-7} }