Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS

@inproceedings{Wong2016CandidateEG,
  title={Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS},
  author={Y. Wong and Moataz Abd El Ghany and Raeece Naeem and Kok-Wei Lee and Yung-Chie Tan and Arnab Pain and Sheila Nathan},
  booktitle={Front. Microbiol.},
  year={2016}
}
Burkholderia cenocepacia infection often leads to fatal cepacia syndrome in cystic fibrosis patients. However, antibiotic therapy rarely results in complete eradication of the pathogen due to its intrinsic resistance to many clinically available antibiotics. Recent attention has turned to the identification of essential genes as the proteins encoded by these genes may serve as potential targets for development of novel antimicrobials. In this study, we utilized TraDIS (Transposon Directed… CONTINUE READING
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