Candidate's Thesis: The Application of Sentinel Node Radiolocalization to Solid Tumors of the Head and Neck: A 10‐Year Experience

@article{Alex2004CandidatesTT,
  title={Candidate's Thesis: The Application of Sentinel Node Radiolocalization to Solid Tumors of the Head and Neck: A 10‐Year Experience},
  author={James C. Alex},
  journal={The Laryngoscope},
  year={2004},
  volume={114}
}
  • J. C. Alex
  • Published 1 January 2004
  • Medicine
  • The Laryngoscope
Objectives/Hypothesis The goals of the research study were to develop an easily mastered, accurate, minimally invasive technique of sentinel node radiolocalization with biopsy (SNRLB) in the feline model; to compare it with blue‐dye mapping techniques; and to test the applicability of sentinel node radiolocalization biopsy in three head and neck tumor types: N0 malignant melanoma, N0 Merkel cell carcinoma, and N0 squamous cell carcinoma. 

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Joint practice guidelines for radionuclide lymphoscintigraphy for sentinel node localization in oral/oropharyngeal squamous cell carcinoma

TLDR
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Surgery must define its role in the multidisciplinary treatment of advanced cancers, which currently often favors (chemo)radiotherapy protocols.

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TLDR
The data provide a certain degree of evidence that, due to its high sensitivity, the SNB procedure can be applied to the initial stages of OSCC.

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  • P. RichardsT. Peacock
  • Medicine
    Cancer imaging : the official publication of the International Cancer Imaging Society
  • 2007
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Sentinel node biopsy and head and neck tumors—Where do we stand today?

TLDR
It is concluded that certain tumor types that have a known propensity for aggressive behavior are the best candidates for trials employing sentinel node sampling and candidates include many cutaneous melanomas of the head and neck, oropharyngeal squamous carcinomas, and selected thyroid carcinomas.

Diagnostic efficacy of sentinel node biopsy in oral squamous cell carcinoma. Cohort study and meta-analysis.

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The data provide a certain degree of evidence that, due to its high sensitivity, the SNB procedure can be applied to the initial stages of OSCC.
...

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The aim of this article is to correlate the anatomic distribution of pathologically involved lymph nodes with primary melanoma sites and to compare these findings with clinically predicted patterns of metastatic spread.

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