Candidate's thesis: Platelet-activating factor-induced hearing loss: mediated by nitric oxide?

@article{Rhee2003CandidatesTP,
  title={Candidate's thesis: Platelet-activating factor-induced hearing loss: mediated by nitric oxide?},
  author={C K Rhee},
  journal={The Laryngoscope},
  year={2003},
  volume={113 12},
  pages={2059-66}
}
  • C K Rhee
  • Published 2003 in The Laryngoscope
OBJECTIVES/HYPOTHESIS Platelet-activating factor (PAF)in middle ear effusion is thought to induce hearing loss. The purpose of this study is to investigate the role of nitric oxide (NO) in the mechanism of PAF-induced hearing loss by studying the effects of PAF application on the round window membrane (RWM) with and without PAF-antagonist NO-blocker. STUDY DESIGN Longitudinal study on randomized guinea pigs using PAF to induce hearing loss. METHODS Guinea pigs were divided into four groups… CONTINUE READING