A 63-year-old man with a history of COPD, hepatitis C and chronic alcoholism underwent a scheduled vascular surgery. Post-operatively, he was admitted in the ICU for delirium for 2 weeks where a central venous catheter was placed. Upon discharge, he resumed his light duty work. Four weeks later, he started having low back pain after lifting his toddler son. He was treated symptomatically by emergency room physicians for 1 month and ultimately was referred to the outpatient clinic. He complained about low-grade continuous, non-radiating low back pain. He denied fever or malaise. Upon physical examination, he had tenderness over the T8-9 level with an apparent kyphotic deformity, but his neurological exam was normal. Laboratory tests were normal except elevated ESR and showed no immunosuppression. Thoracic spine radiographs revealed acute compression fractures of vertebral bodies at T8, T9 levels. CT-scan and later, MRI confirmed spondylodiscitis [Figures 1 and 2]. The CT-guided biopsy revealed Candida albicans infection. He was started on caspofungin for 7 days followed by fluconazole treatment for 6 months until he had clinical resolution with normalization of ESR.