Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway.

@article{Ifrim2013CandidaAP,
  title={Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway.},
  author={Daniela C. Ifrim and Leo A B Joosten and B. -J. Kullberg and Liesbeth E. H. Jacobs and Trees J. G. Jansen and David M. L. Williams and Neil A R Gow and Jos W M van der Meer and Mihai G Netea and Jessica Quintin},
  journal={Journal of immunology},
  year={2013},
  volume={190 8},
  pages={4129-35}
}
The immune system is essential to maintain homeostasis with resident microbial populations, ensuring that the symbiotic host-microbial relationship is maintained. In parallel, commensal microbes significantly shape mammalian immunity at the host mucosal surface, as well as systemically. Candida albicans is an opportunistic pathogen that lives as a commensal… CONTINUE READING