Candida albicans TDH3 gene promotes secretion of internal invertase when expressed in Saccharomyces cerevisiae as a glyceraldehyde-3-phosphate dehydrogenase-invertase fusion protein.

@article{Delgado2003CandidaAT,
  title={Candida albicans TDH3 gene promotes secretion of internal invertase when expressed in Saccharomyces cerevisiae as a glyceraldehyde-3-phosphate dehydrogenase-invertase fusion protein.},
  author={Mar{\'i}a Luisa Delgado and Mar{\'i}a Luisa Mal{\'e} Gil and Daniel Gozalbo},
  journal={Yeast},
  year={2003},
  volume={20 8},
  pages={713-22}
}
We have checked the ability of the Candida albicans GAPDH polypeptide, which lacks a conventional N-terminal signal peptide, to reach the cell wall in Saccharomyces cerevisiae by using an intracellular form of the yeast invertase as a reporter protein. A hybrid TDH3-SUC2 gene containing the C. albicans TDH3 promoter sequences and a coding region encoding a… CONTINUE READING