Candida albicans Morphogenesis Is Not Required for Macrophage Interleukin 1β Production

  title={Candida albicans Morphogenesis Is Not Required for Macrophage Interleukin 1β Production},
  author={Melanie A Wellington and Kristy A Koselny and Damian J Krysan},
UNLABELLED The interaction of Candida albicans with macrophages induces the production of interleukin 1β (IL-1β) through inflammasome activation in a process that is required for host survival. C. albicans hypha formation has been linked to IL-1β production, but the question of whether hyphae are sufficient to trigger IL-1β production has not been examined directly. To address this question, a C. albicans library of 165 transcription factor deletion mutants was screened for strains with altered… CONTINUE READING
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An introduction to the medically important Candida species, p. 11–25

GP Moran, D Coleman, D. Sullivan
Candida and candidiasis, • 2012

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