Candida albicans HSP12 is co-regulated by physiological CO2 and pH.

@article{Sheth2008CandidaAH,
  title={Candida albicans HSP12 is co-regulated by physiological CO2 and pH.},
  author={Chirag C. Sheth and Estelle Gewiss Mogensen and Man Shun Fu and Ian C. Blomfield and Fritz A. M{\"u}hlschlegel},
  journal={Fungal genetics and biology : FG & B},
  year={2008},
  volume={45 7},
  pages={1075-80}
}
Global transcriptional analysis of Candida albicans exposed to elevated ambient CO(2) revealed a statistically significant differential regulation of 14 genes. Subsequent RNA hybridisation analysis of one gene, HSP12, confirmed CO(2)-regulation via a cAMP-dependent mechanism. Additionally, Northern analyses and gel mobility shift assays demonstrate the co-regulation of HSP12 by environmental pH via a Rim101-dependent mechanism.