Candesartan cilexetil in children with hypertension or proteinuria: preliminary data

  title={Candesartan cilexetil in children with hypertension or proteinuria: preliminary data},
  author={Giacomo Domenico Simonetti and Rodo O. von Vigier and Martin A Konrad and Mattia Rizzi and Emilio Filippo Fossali and Mario G Bianchetti},
  journal={Pediatric Nephrology},
The angiotensin II receptor blockers irbesartan and losartan effectively reduce blood pressure and proteinuria in childhood. We were impressed by the neutral taste and the small size of the candesartan cilexetil tablets. This angiotensin II receptor blocker was used during 4 months in 17 pediatric patients (aged 0.5–16, median 4.5 years) with chronic arterial hypertension (n=6), overt proteinuria (n=2), or both (n=9). The initial candesartan dose of 0.23 (0.16–0.28) mg/kg body weight once daily… CONTINUE READING

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