Candesartan cilexetil: an update of its use in essential hypertension.

@article{Easthope2002CandesartanCA,
  title={Candesartan cilexetil: an update of its use in essential hypertension.},
  author={Stephanie E. Easthope and Blair Jarvis},
  journal={Drugs},
  year={2002},
  volume={62 8},
  pages={1253-87}
}
UNLABELLED Candesartan cilexetil is converted to the angiotensin II receptor antagonist candesartan during absorption from the gastrointestinal tract. The selective and competitive binding of candesartan to the angiotensin II type 1 (AT(1)) receptor prevents binding of angiotensin II, a key mediator in the renin-angiotensin system. Significant reductions in… CONTINUE READING