Cancerous, but not stromal, thrombospondin-2 contributes prognosis in pulmonary adenocarcinoma.

@article{Chijiwa2009CancerousBN,
  title={Cancerous, but not stromal, thrombospondin-2 contributes prognosis in pulmonary adenocarcinoma.},
  author={Tsuyoshi Chijiwa and Yoshiyuki Abe and Yoshimasa Inoue and Hozumi Matsumoto and Kenji Kawai and Masahiro Matsuyama and Noriyuki Miyazaki and Hiroshi Inoue and Masaya Mukai and Y. Ueyama and Masato Nakamura},
  journal={Oncology reports},
  year={2009},
  volume={22 2},
  pages={
          279-83
        }
}
Thrombospondin (TSP)-2 is known to be an endogenous negative regulator of vascularization in human cancer. However, it is unclear whether TSP-2 expression is related to neovascularization and prognosis in non-small cell lung cancer. In this study, we quantitatively examined the expression of TSP-2 mRNA by real-time reverse transcription-polymerase chain reaction (RT-PCR) in 102 pulmonary adenocarcinomas. All 102 carcinoma specimens expressed TSP-2 mRNA. The expression of TSP-2 mRNA in carcinoma… CONTINUE READING

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