Cancerogenesis in Helicobacter pylori infected stomach--role of growth factors, apoptosis and cyclooxygenases.

  title={Cancerogenesis in Helicobacter pylori infected stomach--role of growth factors, apoptosis and cyclooxygenases.},
  author={Peter C. Konturek and Stanisław Jan Konturek and Piotr Pierzchalski and Wladyslaw Bielański and Alexandra Duda and Krzysztof Marlicz and Teresa Starzyńska and Eckhart Georg Hahn},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  volume={7 5},
BACKGROUND Epidemiological and animal studies demonstrated a link between gastric cancer (GC) or mucosal associated lymphoid tissue (MALT) lymphoma and chronic infection with Helicobacter pylori (H. pylori). The exact mechanism responsible for the development of GC and MALT-lymphoma in H. pylori-infected patients still remains obscure. This report is designed to overview the molecular biology, especially the gene expression and histochemical manifestation of gastrin and other growth factors… CONTINUE READING


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