Cancer vaccines: preclinical studies and novel strategies.

  title={Cancer vaccines: preclinical studies and novel strategies.},
  author={Claudia M Palena and Scott I Abrams and Jeffrey Schlom and James W Hodge},
  journal={Advances in cancer research},
The development of cancer vaccines, aimed to enhance the immune response against a tumor, is a promising area of research. A better understanding of both the molecular mechanisms that govern the generation of an effective immune response and the biology of a tumor has contributed to substantial progress in the field. Areas of intense investigation in cancer immunotherapy will be discussed here, including: (1) the discovery and characterization of novel tumor antigens to be used as targets for… CONTINUE READING
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