Cancer therapy with combinations of biological response modifiers and cytotoxics: an update.

@article{Borden1990CancerTW,
  title={Cancer therapy with combinations of biological response modifiers and cytotoxics: an update.},
  author={Ernest C. Borden and Stephen P. Creekmore},
  journal={Cancer cells},
  year={1990},
  volume={2 7},
  pages={217-20}
}
The pleiotropic effects of BRMs on cell function emerged as one of the more prominent themes at this conference. As we continue to learn more about the mechanisms of action of BRMs, it seems likely that this aspect of their biology will one day be used for therapeutic gain. Conceivably, by varying the dose and schedule of a single BRM, it may be possible to… CONTINUE READING