Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation.

@article{Atanackovic2007CancertestisAA,
  title={Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation.},
  author={Djordje Atanackovic and Julia Arfsten and Yanran Cao and Sacha Gnjatic and Frank Schnieders and Katrin Bartels and Georgia Schilling and Christiane Faltz and Christine Wolschke and Judith Dierlamm and Gerd Ritter and Thomas H. Eiermann and Dieter Kurt Hossfeld and Axel Rolf Zander and Achim A. Jungbluth and L. John Old and C Carsten Bokemeyer and Nicolaus Kr{\"o}ger},
  journal={Blood},
  year={2007},
  volume={109 3},
  pages={1103-12}
}
Immunotherapies using cancer-testis (CT) antigens as targets represent a potentially useful treatment in patients with multiple myeloma (MM) who commonly show recurrent disease following chemotherapy. We analyzed the expression of 11 CT antigens in bone marrow samples from patients with MM (n=55) and healthy donors (n=32) using reverse transcriptase-polymerase chain reaction (RT-PCR). CT antigens were frequently expressed in MM with 56% (MAGEC2), 55% (MAGEA3), 35% (SSX1), 20% (SSX4, SSX5), 16… CONTINUE READING

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