Cancer stem cells in haematological malignancies

  title={Cancer stem cells in haematological malignancies},
  author={Radoslaw Zagozdzon and Jakub Goląb},
  booktitle={Contemporary oncology},
At least several types of human haematological malignancies can now be seen as 'stem-cell diseases'. The best-studied in this context is acute myeloid leukaemia (AML). It has been shown that these diseases are driven by a pool of 'leukaemia stem cells (LSC)', which remain in the quiescent state, have the capacity to survive and self-renew, and are responsible for the recurrence of cancer after classical chemotherapy. It has been understood that LSC must be eliminated in order to cure patients… CONTINUE READING
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