Cancer stem cells in haematological malignancies

@inproceedings{Zagozdzon2015CancerSC,
  title={Cancer stem cells in haematological malignancies},
  author={Radoslaw Zagozdzon and Jakub Goląb},
  booktitle={Contemporary oncology},
  year={2015}
}
At least several types of human haematological malignancies can now be seen as 'stem-cell diseases'. The best-studied in this context is acute myeloid leukaemia (AML). It has been shown that these diseases are driven by a pool of 'leukaemia stem cells (LSC)', which remain in the quiescent state, have the capacity to survive and self-renew, and are responsible for the recurrence of cancer after classical chemotherapy. It has been understood that LSC must be eliminated in order to cure patients… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Expression of the target receptor CD33 in CD34+/CD38-/CD123+ AML stem cells.

European journal of clinical investigation • 2007
View 5 Excerpts
Highly Influenced

The variety of leuke ­ mic stem cells in myeloid malignancy

DH Wiseman, BF Greystoke, Somervaille TCP
Oncogene • 2014

Similar Papers

Loading similar papers…