Cancer stem cells, tumor dormancy, and metastasis

  title={Cancer stem cells, tumor dormancy, and metastasis},
  author={Purvi Patel and Emily I. Chen},
  booktitle={Front. Endocrin.},
Tumor cells can persist undetectably for an extended period of time in primary tumors and in disseminated cancer cells. Very little is known about why and how these tumors persist for extended periods of time and then evolve to malignancy. The discovery of cancer stem cells (CSCs) in human tumors challenges our current understanding of tumor recurrence… CONTINUE READING