Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.

@article{Hale2014CancerSC,
  title={Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.},
  author={James Scott Hale and Balint Istvan Otvos and Maksim Sinyuk and Alvaro G. Alvarado and Masahiro Hitomi and Kevin B. Stoltz and Qiulian Wu and William A Flavahan and Bruce S Levison and Mette L. Johansen and David Schmitt and Janna Neltner and Ping Huang and Bin Ren and Andrew E. Sloan and Roy L Silverstein and Candece L Gladson and Joseph A. DiDonato and Jonathan Mark Brown and Thomas M McIntyre and Stanley L. Hazen and Craig Horbinski and Jeremy Rich and Justin D Lathia},
  journal={Stem cells},
  year={2014},
  volume={32 7},
  pages={
          1746-58
        }
}
Glioblastoma (GBM) contains a self-renewing, tumorigenic cancer stem cell (CSC) population which contributes to tumor propagation and therapeutic resistance. While the tumor microenvironment is essential to CSC self-renewal, the mechanisms by which CSCs sense and respond to microenvironmental conditions are poorly understood. Scavenger receptors are a broad class of membrane receptors well characterized on immune cells and instrumental in sensing apoptotic cellular debris and modified lipids… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Emerging role of lipid metabolism alterations in Cancer stem cells

Mei Yi, Junjun Li, +10 authors Bo Xiang
  • Journal of experimental & clinical cancer research : CR
  • 2018
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Identification of the Gene Expression Rules That Define the Subtypes in Glioma

Yu-Dong Cai, Shiqi Zhang, +5 authors Xiangyin Kong
  • Journal of clinical medicine
  • 2018
VIEW 1 EXCERPT
CITES RESULTS

Similar Papers

Loading similar papers…