Cancer revoked: oncogenes as therapeutic targets

@article{Felsher2003CancerRO,
  title={Cancer revoked: oncogenes as therapeutic targets},
  author={Dean W. Felsher},
  journal={Nature Reviews Cancer},
  year={2003},
  volume={3},
  pages={375-379}
}
Recent findings show that even the brief inactivation of a single oncogene might be sufficient to result in the sustained loss of a neoplastic phenotype. It is therefore possible that the targeted inactivation of oncogenes could be a specific and effective treatment for cancer. So why does oncogene inactivation cause tumour regression and will this be a generally successful approach for the treatment of human neoplasia? 

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