Cancer pain therapy with a fixed combination of prolonged-release oxycodone/naloxone: results from a non-interventional study

@inproceedings{Nolte2013CancerPT,
  title={Cancer pain therapy with a fixed combination of prolonged-release oxycodone/naloxone: results from a non-interventional study},
  author={Thomas Nolte and Ulf Schutter and Oliver Loewenstein},
  booktitle={Pragmatic and observational research},
  year={2013}
}
BACKGROUND Strong opioids, including oxycodone, are the most effective analgesics used to combat moderate to severe cancer pain, but opioid-induced bowel dysfunction is a relevant problem associated with the therapy. Clinical studies have demonstrated equivalent analgesic efficacy and improved bowel function in treatment with a fixed combination of prolonged-release (PR) oxycodone and PR naloxone compared to oxycodone alone in patients with nonmalignant pain. Here, we report of a prospective… CONTINUE READING
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