Cancer of unknown primary site: still an entity, a biological mystery and a metastatic model

@article{Greco2014CancerOU,
  title={Cancer of unknown primary site: still an entity, a biological mystery and a metastatic model},
  author={Frank Anthony Greco},
  journal={Nature Reviews Cancer},
  year={2014},
  volume={14},
  pages={3-4}
}
Cancer of unknown primary site (CUP) has frustrated patients, their families and physicians for decades because appropriate therapies for patients with metastatic cancers are determined by the primary site or the tissue of origin. Now that we have methods to identify the tissue of origin for the majority of these patients, additional clinical and biological questions are being asked and addressed. 
Recent Discussions
This paper has been referenced on Twitter 7 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
6 Extracted Citations
11 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 11 references

a prospective trial of the Sarah Cannon Research Institute

  • Hainsworth, J. D. et al. Molecular gene expression profiling to p origin, direct site-specific therapy in patients with carcinoma o site
  • J. Clin. Oncol. 31, 217–223
  • 2013

accuracy and ability to complement standard pathology

  • Greco, F. A. et al. Molecular profiling diagnosis in unknown cancer
  • J. Natl Cancer Inst. 105, 782–790
  • 2013

useful in patient management

  • Greco, F. A. Molecular diagnosis of the tissue of origin in site
  • Curr. Treat Options Oncol. http://dx.doi.org/10…
  • 2013

facing individual complexities underlying hallmark capabilities

  • M. DePalma, Hanahan, D. The biology of personalized cancer medicine
  • Mol. Oncol. 6, 111–127
  • 2012

Principles and Practice of Oncology (eds DeVita, V

  • F. A. Greco, Hainsworth, J. D. in Cancer
  • T. Jr et al.) 9th edn 2033–2051
  • 2011

Similar Papers

Loading similar papers…