Cancer metabolism: current perspectives and future directions

  title={Cancer metabolism: current perspectives and future directions},
  author={Cristina Mu{\~n}oz-Pinedo and Nadia El Mjiyad and J-E Ricci},
  booktitle={Cell Death and Disease},
Cellular metabolism influences life and death decisions. An emerging theme in cancer biology is that metabolic regulation is intricately linked to cancer progression. In part, this is due to the fact that proliferation is tightly regulated by availability of nutrients. Mitogenic signals promote nutrient uptake and synthesis of DNA, RNA, proteins and lipids. Therefore, it seems straight-forward that oncogenes, that often promote proliferation, also promote metabolic changes. In this review we… CONTINUE READING
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