Cancer invasion and metastasis.

  title={Cancer invasion and metastasis.},
  author={Christian Wittekind and Matthias Neid},
  volume={69 Suppl 1},
Metastasis is the transfer of malignant tumors from one organ to a distant organ. It is the most common cause of death in cancer patients. Different molecular mechanisms enable tumor cells to infiltrate the surrounding tissue, invade blood vessels and leave the blood stream at a different site. Tumor cell interaction with extracellular matrix components and epithelial-mesenchymal transition as well as angiogenesis are important factors in invasion and metastasis. Gene expression profiles of… CONTINUE READING

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