Cancer incidence in the first-degree relatives of ovarian cancer patients.

@article{Auranen1996CancerII,
  title={Cancer incidence in the first-degree relatives of ovarian cancer patients.},
  author={Annika Auranen and Eero I Pukkala and Juha I M{\"a}kinen and Risto Sankila and Seija Gr{\'e}nman and Tuula Anneli Salmi},
  journal={British Journal of Cancer},
  year={1996},
  volume={74},
  pages={280 - 284}
}
Cancer incidence was studied among 3072 first-degree relatives of 559 unselected ovarian cancer patients. Among cohort members there were 306 cancer cases. The overall cancer incidence was not increased: the standardised incidence ratio (SIR) in males was 0.9 (95% confidence interval 0.8-1.1) and in females 1.0 (0.8-1.1). The female relatives had a significantly increased risk for ovarian cancer (SIR 2.8, 1.8-4.2). The excess was attributable to sisters only (SIR 3.7, 2.3-5.7). The relative… CONTINUE READING