Cancer in twins: genetic and nongenetic familial risk factors.

  title={Cancer in twins: genetic and nongenetic familial risk factors.},
  author={Anders Ahlbom and Paul Lichtenstein and Hans Malmstr{\"o}m and Maria Feychting and Kari Hemminki and Nancy L Pedersen},
  journal={Journal of the National Cancer Institute},
  volume={89 4},
BACKGROUND Familial clustering has been observed for cancers that occur at specific sites. Most findings, which leave little doubt about the involvement of a heritable (i.e., genetic) component in the development of some cancers, are based on data from "cancer-prone" families or interviews with subjects who have cancer. The study of twins should be of value in cancer epidemiology because twins either are genetically identical or share half of their segregating genes. PURPOSE We linked the… CONTINUE READING


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