Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion.

@article{Schreiber2011CancerII,
  title={Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion.},
  author={Robert D Schreiber and L. John Old and Mark J Smyth},
  journal={Science},
  year={2011},
  volume={331 6024},
  pages={1565-70}
}
Understanding how the immune system affects cancer development and progression has been one of the most challenging questions in immunology. Research over the past two decades has helped explain why the answer to this question has evaded us for so long. We now appreciate that the immune system plays a dual role in cancer: It can not only suppress tumor growth by destroying cancer cells or inhibiting their outgrowth but also promote tumor progression either by selecting for tumor cells that are… CONTINUE READING
Highly Influential
This paper has highly influenced 64 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 1,381 extracted citations

Biomarkers of the Tumor Microenvironment

Springer International Publishing • 2017
View 7 Excerpts
Highly Influenced

Coevolution of Leukemia and Host Immune Cells in Chronic Lymphocytic Leukemia.

Cold Spring Harbor perspectives in medicine • 2017
View 5 Excerpts
Highly Influenced

Mechanisms governing metastatic dormancy in breast cancer.

Seminars in cancer biology • 2017
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-2 of 2 references

Cellular and Humoral Aspects of the Hypersensitive States

L. Thomas
1959
View 1 Excerpt

Kershaw for invaluable advice and contributions to this review

M.H.M.D. Vesely
VOL 331 SCIENCE www.sciencemag.org • 1203

Similar Papers

Loading similar papers…