Cancer driver mutations in protein kinase genes.

Abstract

Recent studies investigating the genetic determinants of cancer suggest that some of the genetic alterations contributing to tumorigenesis may be inherited, but the vast majority is somatically acquired during the transition of a normal cell to a cancer cell. A systematic understanding of the genetic and molecular determinants of cancers has already begun… (More)
DOI: 10.1016/j.canlet.2008.11.008

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Cite this paper

@article{Torkamani2009CancerDM, title={Cancer driver mutations in protein kinase genes.}, author={Ali Torkamani and Gennady M Verkhivker and Nicholas J. Schork}, journal={Cancer letters}, year={2009}, volume={281 2}, pages={117-27} }