• Corpus ID: 26454713

Cancer chemopreventive potential of the Egyptian flaxseed oil in a rat colon carcinogenesis bioassay--implications for its mechanism of action.

  title={Cancer chemopreventive potential of the Egyptian flaxseed oil in a rat colon carcinogenesis bioassay--implications for its mechanism of action.},
  author={Elsayed I. Salim and Ahlam E Abou-Shafey and Ahmed Masoud and Salwa A Elgendy},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  volume={12 9},
The possible chemopreventive effects of natural Egyptian flaxseed oil on preneoplasia and cancer formation were investigated in a rat medium-term colon carcinogenesis bioassay. Male Wistar rats were divided into 6 groups. Groups 1, 3 and 5 were initiated by 1,2-dimethylhydrazine (DMH) 20 mg/kg body weight s.c. 8 times, twice a week to initiate colon carcinogenesis. Groups 1 and 3 received 20% or 5% flaxseed oil respectively in diet in post initiation stage until the end. Groups 2 and 4 served… 

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