Cancer chemopreventive activity of odorine and odorinol from Aglaia odorata.

@article{Inad2001CancerCA,
  title={Cancer chemopreventive activity of odorine and odorinol from Aglaia odorata.},
  author={A Inad and Hoyoku Nishino and Masashi Kuchide and Junko Takayasu and Teruo Mukainaka and Yoshitoshi Nobukuni and Masato Okuda and Harukuni Tokuda},
  journal={Biological \& pharmaceutical bulletin},
  year={2001},
  volume={24 11},
  pages={
          1282-5
        }
}
In the course of our continuing search for novel cancer chemo-preventive agents from natural sources, we have carried out a primary screening in vitro assay of the compounds isolated from Aglaia odorata. Consequently, aminopyrrolidine-diamides, odorine and odorinol, were obtained as active constituents. These compounds exhibited potent anti-carcinogenic effects in a two-stage carcinogenesis test of mouse skin induced by 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and 12-O… 
Chemical Constituents of Aglaia odorata Leaves and Their Anti-inflammatory Effects
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Comparative phytochemistry of flavaglines (= rocaglamides), a group of highly bioactive flavolignans from Aglaia species (Meliaceae)
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  • Medicine
    Phytochemistry reviews : proceedings of the Phytochemical Society of Europe
  • 2021
TLDR
Broad-based comparison revealed characteristic substitution trends which contribute as chemical markers to natural delimitation and grouping of taxonomically problematic Aglaia species and were shown to be not only promising anticancer agents but gained now also high expectations as agents against emerging RNA viruses like SARS-CoV-2.
Absolute configuration of odorine
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The title compound, known as odorine or roxburghiline, is a nitrogenous compound isolated from the leaves of Aglaia odorata and the absolute configuration was determined by refinement of the Flack parameter with data collected using Cu Kα radiation showing positions 2 and 2′ to be S and R, respectively.
Photodynamic therapeutic role of indocyanine green in tumor-associated inflammation in skin cancer.
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The proposed ICG/PDT treatment modality showed a significant anti-tumor and anti-inflammatory activity against skin cancer accompanied with COX-2 elevation.
Peroxide values of Aglaia argentea Blume, A. silvestria (M. Roemer) Merr., and A. tomentosa Teijsm. & Binn.
The objectives of this research were to determine the chemical components and the peroxide values of three Aglaia species (A. argentea Blume, A. silvestria (M. Roemer) Merr and A. tomentosa Teijsm &
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