Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models

@article{Zhang2004CancerCA,
  title={Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models},
  author={Z. Zhang and Y. Wang and R. Yao and J. Li and Y. Yan and M. Regina and William L Lemon and C. Grubbs and R. Lubet and M. You},
  journal={Oncogene},
  year={2004},
  volume={23},
  pages={3841-3850}
}
  • Z. Zhang, Y. Wang, +7 authors M. You
  • Published 2004
  • Biology, Medicine
  • Oncogene
    • Antitumor B (ATB), also known as Zeng Sheng Ping, is a Chinese herbal mixture composed of six plants. Previously, clinical studies have shown a significant chemopreventive efficacy of ATB against human esophageal and lung cancers. In the present study, A/J mice harboring a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf and treated with benzo[a]pyrene were used to investigate the chemopreventive effects of ATB on chemically induced lung tumorigenesis. Mice with various genotypes… CONTINUE READING
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    Paper Mentions

    Observational Clinical Trial
    Pharmacokinetics Study of Antitumor B in Healthy Volunteers
    The purpose of this study is to evaluate the single-dose oral pharmacokinetics of an herbal supplement - Antitumor B - in healthy subjects.  
    ConditionsHealthy Adults
    InterventionDietary Supplement
    University of Houston
    December 2019 - June 2020
    54 Citations
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