Cancer chemoprevention with dietary isothiocyanates mature for clinical translational research.

@article{Singh2012CancerCW,
  title={Cancer chemoprevention with dietary isothiocyanates mature for clinical translational research.},
  author={Shivendra V Singh and Kamayani Singh},
  journal={Carcinogenesis},
  year={2012},
  volume={33 10},
  pages={1833-42}
}
Inverse association between dietary intake of cruciferous vegetables and cancer risk observed in population-based case-control studies is partly attributable to structurally simple but mechanistically complex phytochemicals with an isothiocyanate (-N=C=S) functional group. Cancer protective role for dietary isothiocyanates (ITCs) is substantiated by preclinical studies in rodent models. A common feature of many naturally occurring ITCs relates to their ability to cause growth arrest and cell… CONTINUE READING

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