Cancer cachexia and targeting chronic inflammation: a unified approach to cancer treatment and palliative/supportive care.

@article{Macdonald2007CancerCA,
  title={Cancer cachexia and targeting chronic inflammation: a unified approach to cancer treatment and palliative/supportive care.},
  author={Neil W. Macdonald},
  journal={The journal of supportive oncology},
  year={2007},
  volume={5 4},
  pages={
          157-62; discussion 164-6, 183
        }
}
Chronic inflammation often acts as a tumor promoter, resulting in aggressive cancerous growth and spread. Many of the same inflammatory factors that promote tumor growth also are responsible for cancer cachexia/anorexia, pain, debilitation, and shortened survival. A compelling case may be made for mounting an attack on inflammation with other anticancer measures at initial diagnosis, with the consequent probability of improving both patient quality of life and survival. High serum levels of the… CONTINUE READING

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