Cancer cachexia’s metabolic signature in a murine model confirms a distinct entity

@article{DerTorossian2012CancerCM,
  title={Cancer cachexia’s metabolic signature in a murine model confirms a distinct entity},
  author={Hirak Der-Torossian and Scott A. Asher and Jason H. Winnike and Ashley Wysong and Xiaoying Yin and Monte S Willis and Thomas M. O’Connell and Marion E. Couch},
  journal={Metabolomics},
  year={2012},
  volume={9},
  pages={730-739}
}
Despite recent consensus definitions, lack of specific biomarkers remains a hurdle towards a more accurate and efficient diagnosis of cancer cachexia, distinguishing cachexia as a separate entity from other wasting syndromes. In a previous pilot study, we have shown that cancer-cachectic mice have a unique metabolic fingerprint with distinct glucose and lipid alterations compared to healthy controls. Further metabolomics studies were carried out to investigate differences in metabolic profiles… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

Cachexia

D. P. Kotler
  • Annals of Internal Medicine
  • 2000
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

What is cancer

N. Bennani-Baiti, D. Walsh
  • 2009
VIEW 2 EXCERPTS

Similar Papers

Loading similar papers…