Cancer cachexia: rationale for the MENAC (Multimodal—Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial

@article{Solheim2018CancerCR,
  title={Cancer cachexia: rationale for the MENAC (Multimodal—Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial},
  author={T. Solheim and B. Laird and T. R. Balstad and A. Bye and G. Stene and V. Baracos and F. Strasser and G. Griffiths and M. Maddocks and M. Fallon and S. Kaasa and K. Fearon},
  journal={BMJ Supportive & Palliative Care},
  year={2018},
  volume={8},
  pages={258 - 265}
}
Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a major impact on patient physical function, morbidity and mortality. Despite the consequences of cachexia, there is no licensed treatment for cachexia and no accepted standard of care. It has been argued that the multifactorial genesis of cachexia lends itself to therapeutic… Expand
62 Citations

Paper Mentions

Interventional Clinical Trial
Cancer cachexia is a multi-factorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional… Expand
ConditionsCachexia, Neoplasms
InterventionDrug, Other
Diet-related interventions for cancer-associated cachexia
Combination therapy in cachexia.
  • 2
Cancer Cachexia and Related Metabolic Dysfunction
  • 12
  • PDF
What are the criteria for response to cachexia treatment?
  • 9
Investigational drugs for the treatment of cancer cachexia: a focus on phase I and phase II clinical trials
  • 4
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 73 REFERENCES
Cancer cachexia: developing multimodal therapy for a multidimensional problem.
  • K. Fearon
  • Medicine
  • European journal of cancer
  • 2008
  • 329
Are there any benefits of exercise training in cancer cachexia?
  • 95
  • PDF
Evidence base for multimodal therapy in cachexia
  • 36
Immunological and hormonal effects of exercise: implications for cancer cachexia
  • 31
Exercise for cancer cachexia in adults.
  • 45
  • PDF
...
1
2
3
4
5
...