Cancer biology for individualized therapy: correlation of growth fraction index in native-state histoculture with tumor grade and stage.

@article{Vescio1990CancerBF,
  title={Cancer biology for individualized therapy: correlation of growth fraction index in native-state histoculture with tumor grade and stage.},
  author={Robert A. Vescio and Kenneth M. Connors and Tyler Youngkin and Gerald M. Bordin and James A. Robb and Jay N. Umbreit and Robert M Hoffman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 2},
  pages={691-5}
}
There is a need for individualization of all aspects of cancer therapy. Because of significant heterogeneity within a tumor class, there is a need to develop an in vitro test to accurately gauge tumor aggressiveness. Such a measurement would greatly aid treatment decision making. Current methodologies such as flow cytometry, which lacks unambiguous interpretation of cell-proliferative data, and determination of the thymidine-labeling index, which measures nucleotide uptake in a nonphysiological… CONTINUE READING
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…