Cancer-associated cachexia

  title={Cancer-associated cachexia},
  author={Vickie Baracos and Lisa Martin and Murray Korc and Denis C. Guttridge and Kenneth C. H. Fearon},
  journal={Nature Reviews Disease Primers},
Cancer-associated cachexia is a disorder characterized by loss of body weight with specific losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination of reduced food intake and metabolic changes, including elevated energy expenditure, excess catabolism and inflammation. Cachexia is highly associated with cancers of the pancreas, oesophagus, stomach, lung, liver and bowel; this group of malignancies is responsible for half of all cancer deaths worldwide. Cachexia… CONTINUE READING
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