Cancer and mortality among users and nonusers of snus

  title={Cancer and mortality among users and nonusers of snus},
  author={Ann Roosaar and Anna Louise Viktoria Johansson and Gunilla Sandborgh-Englund and Tony Ax{\'e}ll and Olof Nyrén},
  journal={International Journal of Cancer},
Scandinavian moist snuff (snus) is claimed to be a safer alternative to smoking. We aimed to quantify cancer incidence among male snus users and to shed light on the net health outcome by studying their overall mortality. A cohort, comprised of 9,976 men who participated in a population‐based survey, was compiled in 1973–74. Follow‐up until January 31, 2002, was accomplished through record‐linkages with nation‐wide and essentially complete registers of demographics, cancer and causes of deaths… 

No association between moist oral snuff (snus) use and oral cancer: pooled analysis of nine prospective observational studies

Swedish snus use does not appear to be implicated in the development of oral cancer in men and shared frailty models with random effects at the study level suggest no clear trends in risk with duration or intensity.

Snus use, smoking and survival among prostate cancer patients

Snus use was associated with increased risks of prostate cancer and total mortality among prostate cancer patients, and suggests that tobacco‐related components such as nicotine or tobacco‐specific carcinogens may promote cancer progression independent of tobacco's combustion products.

Summary of the epidemiological evidence relating snus to health.

  • P. Lee
  • Medicine
    Regulatory toxicology and pharmacology : RTP
  • 2011

Relationship between type of smokeless tobacco & risk of cancer: A systematic review

A wide variation was noted in the association of various cancers and specific SLT products based on their nature, methods of use and inherent toxicity, while the majority of chewing tobacco products displayed higher risk for oral and oesophageal cancers while the same was not observed for snus.

Snus: a compelling harm reduction alternative to cigarettes

Prevalence statistics and epidemiological data indicate that the use of snus confers a significant harm reduction benefit which is reflected in the comparatively low levels of tobacco-related disease in Sweden when compared with the rest of Europe.

Tobacco Use, Oral Health, and Risk of Parkinson's Disease

It was found that tobacco use was associated with a lower risk of PD in males, while poor oral health seems not to be associated with PD occurrence.

Swedish snus use is associated with mortality: a pooled analysis of eight prospective studies

Snus use among men is associated with increased all-cause mortality, cardiovascular mortality, with death from other causes and possibly with increased cancer mortality.

Systematic review of the relation between smokeless tobacco and cancer in Europe and North America

An increased risk of oropharyngeal cancer is evident most clearly for past smokeless tobacco use in the USA, but not for Scandinavian snuff, and some meta-analyses suggest a possible effect for oesophagus, pancreas, larynx and kidney cancer, but other cancers show no effect of smokeless Tobacco.

Smokeless tobacco use: a meta-analysis of risk and attributable mortality estimates for India.

SLT use caused over 350,000 deaths in India in 2010, and nearly three-fifth of SLT use-attributable deaths were among women in India, calling for targeted public health intervention focusing on SLT products especially among women.

Aspects of the etiology and survival of lower gastrointestinal cancers

In the first two papers, the Inpatient Register was used to identify patients hospitalized with (i) condylomata acuminata, or with (ii) benign anal lesions. In both papers, the cancer incidence in



A long‐term follow‐up study on the natural course of snus‐induced lesions among Swedish snus users

It is concluded that cancers rarely occur at the site of lesions observed in the distant past in individuals with SILs, which are mucosal changes regularly seen in users of moist snuff (snus).

Swedish Moist Snuff and Myocardial Infarction Among Men

The hypothesis that smokeless tobacco increases the risk for myocardial infarction is not supported in the present study, and among the controls, the consumption of smokeless Tobacco was strongly associated with certain risk factors for my Cardiovascular disease such as smoking, hypertension, and high body mass index.

Oral snuff, smoking habits and alcohol consumption in relation to oral cancer in a Swedish case‐control study

A multivariate analysis suggested that the most important risk factors were beer and liquor consumption, followed by smoking, followedBy smoking, which showed the strongest risk for oral cancer.

Smokeless tobacco use and risk of cancer of the pancreas and other organs

The study suggests that smokeless tobacco products may be carcinogenic on the pancreas and tobacco‐specific N‐nitrosamines are plausible candidates for the carcinogenicity of smokeless Tobacco products in the Pancreas.

Role of snus (oral moist snuff ) in smoking cessation and smoking reduction in Sweden.

By using snus, Swedish male smokers may increase their overall chances of abstinence and suggest that snus is not a necessary component of smoking cessation at the population level.

Smokeless tobacco and oral cancer: a review of the risks and determinants.

  • B. RoduC. Jansson
  • Medicine
    Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists
  • 2004
Research relevant to smokeless tobacco association with oral cancer is reviewed, including epidemiologic studies, studies of putative carcinogens such as tobacco-specific nitrosamines (TSNAs) and other contaminants, and possible cancer inhibitors.

Two large prospective studies of mortality among men who use snuff or chewing tobacco (United States)

These two prospective studies provide limited evidence that current use of chewing tobacco or snuff may increase mortality from heart disease and stroke.

Cigarettes and oral snuff use in Sweden: Prevalence and transitions.

Current cigarette smoking is more prevalent among Swedish women than men, while snus use is more popular among men, and among men who reported using both cigarettes and snus during their life-time, it was more common to quit cigarettes and currently use snus than to quit snus and Currently use cigarettes.