Cancer and Smoking

@article{Fisher1958CancerAS,
  title={Cancer and Smoking},
  author={Ronald Aylmer Sir Fisher},
  journal={Nature},
  year={1958},
  volume={182},
  pages={596-596}
}
THE curious associations with lung cancer found in relation to smoking habits do not, in the minds of some of us, lend themselves easily to the simple conclusion that the products of combustion reaching the surface of the bronchus induce, though after a long interval, the development of a cancer. If, for example, it were possible to infer that smoking cigarettes is a cause of this disease, it would equally be possible to infer on exactly similar grounds that inhaling cigarette smoke was a… 
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References

Lung Cancer and Cigarettes?
TLDR
The association observable between the practice of cigarette smoking and the incidence of cancer of the lung and the Medical Research Council Statistical Unit has been interpreted almost as though it demonstrated a causal connexion between these variables.