Cancer-Targeted Selenium Nanoparticles Sensitize Cancer Cells to Continuous γ Radiation to Achieve Synergetic Chemo-Radiotherapy.

@article{Chan2017CancerTargetedSN,
  title={Cancer-Targeted Selenium Nanoparticles Sensitize Cancer Cells to Continuous γ Radiation to Achieve Synergetic Chemo-Radiotherapy.},
  author={Leung Chan and Lizhen He and Binwei Zhou and Shouhai Guan and Mingjun Bo and Yahui Yang and Ying Liu and Xiao Jun Liu and Yanyang Zhang and Qiang Xie and Tianfeng Chen},
  journal={Chemistry, an Asian journal},
  year={2017},
  volume={12 23},
  pages={
          3053-3060
        }
}
Cancer radiotherapy with 125 I seeds demonstrates higher long-term efficacy and fewer side effects than traditional X-ray radiotherapy owing to its low-dose and continuous radiation but is still limited by radioresistance in clinical applications. Therefore, the design and synthesis of sensitizers that could enhance the sensitivity of cancer cells to 125 I… CONTINUE READING