Cancer Stem Cells in Breast Cancer

  title={Cancer Stem Cells in Breast Cancer},
  author={Ryou-u Takahashi and Fumitaka Takeshita and Tomohiro Fujiwara and Makiko Ono and Takahiro Ochiya},
The cancer stem cell (CSC) theory is generally acknowledged as an important field of cancer research, not only as an academic matter but also as a crucial aspect of clinical practice. CSCs share a variety of biological properties with normal somatic stem cells in self-renewal, the propagation of differentiated progeny, the expression of specific cell markers and stem cell genes, and the utilization of common signaling pathways and the stem cell niche. However, CSCs differ from normal stem cells… CONTINUE READING