Cancer Stem Cells (CSCs) as a Rational Therapeutic Cancer Target, and Screening for CSC-targeting Drugs.

  • Tetsuo Mashima
  • Published 2017 in
    Yakugaku zasshi : Journal of the Pharmaceutical…

Abstract

The emergence of drug resistance is a major obstacle to the successful pharmacological treatment of cancer. Tumor heterogeneity is one of the key factors underlying drug resistance. Cancer cell heterogeneity in tumors is caused by genetic mutation and by the existence of cancer stem cells (CSCs). CSCs are defined as a subpopulation of highly tumorigenic… (More)
DOI: 10.1248/yakushi.16-00229-1

Topics

Cite this paper

@article{Mashima2017CancerSC, title={Cancer Stem Cells (CSCs) as a Rational Therapeutic Cancer Target, and Screening for CSC-targeting Drugs.}, author={Tetsuo Mashima}, journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan}, year={2017}, volume={137 2}, pages={129-132} }