Cancer Stem Cell Properties as Factors Predictive of Chemoresistance in Neoadjuvantly-treated Patients with Ovarian Cancer.

@article{PylvsEerola2016CancerSC,
  title={Cancer Stem Cell Properties as Factors Predictive of Chemoresistance in Neoadjuvantly-treated Patients with Ovarian Cancer.},
  author={Marjo Pylv{\"a}s-Eerola and Annikki K Liakka and Ulla S Puistola and Jussi P Koivunen and Peeter Karihtala},
  journal={Anticancer research},
  year={2016},
  volume={36 7},
  pages={3425-31}
}
BACKGROUND/AIM The nuclear factor erytheroid 2-related factor 2-kelch-like ECH-associated protein (NRF2-KEAP1) system and stem cell-like cancer cells are associated with platinum resistance in ovarian cancer. Our objective was to investigate the possible association between platinum resistance, cellular redox-state regulation and stem cell properties in ovarian cancer. PATIENTS AND METHODS Thirty-eight patients with epithelial ovarian cancer were included. All patients had undergone primary… CONTINUE READING

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