Cancer Malignancy Is Enhanced by Glyceraldehyde-Derived Advanced Glycation End-Products

@inproceedings{Takino2010CancerMI,
  title={Cancer Malignancy Is Enhanced by Glyceraldehyde-Derived Advanced Glycation End-Products},
  author={Jun-ichi Takino and Sho-ichi Yamagishi and Masayoshi Takeuchi},
  booktitle={Journal of oncology},
  year={2010}
}
The receptor for advanced glycation end-products (RAGEs) is associated with the malignancy of cancer. A recent study has suggested that glyceraldehyde-derived AGEs (Glycer-AGEs) enhanced the malignancy of melanoma cells, but glucose-derived AGEs did not. However, the effects of Glycer-AGEs on other cancer cells remain poorly understood, and the molecular mechanisms behind the above-mentioned effect have not been clarified. The present paper aimed to examine the effect of Glycer-AGEs on cultured… CONTINUE READING

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