Cancer: re-evolution of eucaryotic to procaryotic replication units--a result of genetic transposition?

@article{Grossgebauer1983CancerRO,
  title={Cancer: re-evolution of eucaryotic to procaryotic replication units--a result of genetic transposition?},
  author={Klaus Grossgebauer},
  journal={Bio Systems},
  year={1983},
  volume={16 3-4},
  pages={
          253-8
        }
}
We have consistently tried to present our "procaryote-hypothesis" of oncogenesis in the light of evolution. It is suggested that the replication units are the essential starting points of oncogenesis, and cancer is the result of a short and compact re-evolution from eucaryotic to procaryotic replicons. In our view, the process of re-evolution or reactivation of procaryotic replication units and/or their precursors starts with the activity of a cancerogen and proceeds by genetic rearrangements… CONTINUE READING