Cancer: Role of Nutrition, Pathogenesis, Diagnosis and Management

  title={Cancer: Role of Nutrition, Pathogenesis, Diagnosis and Management},
  author={Ahmed M. Kabel and Maaly A. Abd Elmaaboud},
Cancer is characterized by unregulated cell growth. It is one of the most causes of death worldwide. It is attributed to environmental, nutritional and genetic factors. Its clinical presentation varies between local, metastatic and systemic symptoms. Lines of treatment include chemotherapy, radiotherapy and surgical removal. 

Wilms' Tumor of the Kidney: Insights into Risk Factors, Pathogenesis, Diagnosis and Management

Wilms’ tumor is a rare disease of the kidney that usually affects newborn and young children. It is the commonest renal tumor of childhood affecting one in 10,000 children. It may spread into the

Multiple Myeloma: New Perspectives

Multiple myeloma is the most common bone malignancy that occurs frequently in older persons and often has bad prognosis, although advances in therapy resulted in significant improvement in the overall survival rate.

Carcinoma of the Thyroid Gland: Insights into Etiology, Pathogenesis, Diagnosis and Possible Lines of Management

This review sheds light on carcinoma of the thyroid gland in view of the recent trends regarding its prevalence, risk factors, types, clinical picture, methods of diagnosis and possible lines of management.

Hepatocellular Carcinoma: A Focus on the New Lines of Management

New alternative lines of treatment were developed to attack the tumor at the molecular level to improve the prognosis and achieve better results, including check-point inhibitor therapy, molecular targeted therapy and angiogenesis inhibitors.

Carcinoid Tumors: Insights into Etiology, Classification, Clinical Presentation, Prognosis and Management

This review sheds light on the recent perspectives regarding the etiology, classification, clinical presentation, prognosis and management of Carcinoid tumors.

Indole-3-carbinol: A Promising Hope for Cancer Therapy

A mini-review sheds light on the different properties of I3C that make it a promising therapeutic agent for a wide variety of human diseases including cancer.

Astrocytoma: Insights into Risk Factors, Pathogenesis, Diagnosis and Management

Astrocytoma is one of the most common types of brain tumors and can develop in both children and adults and may be treated with surgery, radiation therapy, chemotherapy or a combination of treatments.

Resistance to Anticancer Agents: Recent Trends

This review throws light on resistance of cancer cells to the chemotherapeutic agents in view of the recent trends.

Pituitary Adenomas: Insights into the Recent Trends

  • Ahmed M. Kabel
  • Medicine, Biology
    Journal of Cancer Research and Treatment
  • 2020
This review throws light on pituitary adenoma regarding its prevalence, predisposing factors, types, clinical presentation, diagnosis and possible lines of management in view of the recent trends.



Clinical management of BRCA1 and BRCA2 mutation carriers

Current evidence for strategies to reduce the risks of cancer development in women with BRCA1/2mutations is outlined, and future research directions are discussed.

Cutting off cancer's supply lines

Targeting the blood vessels that feed tumours is not the silver bullet once hoped for, but refinements to the strategy may suggest further ways to treat the disease. Erika Check Hayden reports.

Chronic bacterial and parasitic infections and cancer: a review.

A considerable number of bacterial infections and parasitic infections are associated with the development of cancer, albeit probably not etiopathogenetically.

Lifestyle-related factors and environmental agents causing cancer: an overview.

Comparative study between the effect of methotrexate and valproic acid on solid Ehrlich tumour.

Two genetic hits (more or less) to cancer

Most cancers have many chromosomal abnormalities, both in number and in structure, whereas some show only a single aberration, which indicates that cancers can arise from small numbers of events that affect common cell birth and death processes.

Aetiology of cancer in Asia.

Infectious agents such as Helicobacter pylori, hepatitis B and C viruses, and human papillomavirus were shown to be associated with elevated risks of stomach, liver and cervical cancer, respectively, and environmental exposure to indoor and outdoor air pollution, arsenic, radon, asbestos and second hand smoke was shown to increase the lung cancer risk.

Cancer as an evolutionary and ecological process

The tools of evolutionary biology and ecology are providing new insights into neoplastic progression and the clinical control of cancer.

Drug-Diagnostic Co-Development in Cancer

The targeted clinical trial design allows for an increased success rate in the individual drug-diagnostic co-developments by reducing the failure rate, which in turn will reduce development costs and time, and hence increase the probability of therapeutic and registration success.