Cancer: New delivery platform targets antimirs to tumours

  title={Cancer: New delivery platform targets antimirs to tumours},
  author={Alexandra Flemming},
  journal={Nature Reviews Drug Discovery},
non-coding RNAs that suppress the expression of target genes. Dysregulated miRNAs are known to cause pathology in a range of conditions, and oncomirs (oncogenic miRNAs; a subgroup of miRNAs) can have a causal role in cancer. Therapeutic strategies that use antisense oligomers (antimirs) to silence oncomirs are attractive, but their targeted delivery to tumours is challenging. Now, reporting in Nature, Slack and colleagues introduce a novel delivery platform that targets the acidic… 
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