Cancer: Crossing over to drug resistance

@article{Livingston2008CancerCO,
  title={Cancer: Crossing over to drug resistance},
  author={David M. Livingston and Daniel P. Silver},
  journal={Nature},
  year={2008},
  volume={451},
  pages={1066-1067}
}
1940s, Vladimir Prelog and Mihovil Proštenik made d-quinotoxine from a still-simpler degradation product, homomeroquinene. Woodward and Doering’s contribution was to take the path right back to (relatively) simple starting materials, demonstrating the syn thesis of homomeroquinene from 7-hydroxyisoquino line and then on to d-quinotoxine (Fig. 2). This then… CONTINUE READING
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