Canarypox and fowlpox viruses as recombinant vaccine vectors: an ultrastructural comparative analysis

@article{Pacchioni2010CanarypoxAF,
  title={Canarypox and fowlpox viruses as recombinant vaccine vectors: an ultrastructural comparative analysis},
  author={Sole Maria Pacchioni and Luca Volont{\'e} and Carlo Zanotto and Eleana Pozzi and Carlo Giuli Morghen and Antonia Radaelli},
  journal={Archives of Virology},
  year={2010},
  volume={155},
  pages={915-924}
}
Due to their natural host-range restriction to avian species, canarypox virus (CP) and fowlpox virus (FP) represent efficient and safe vaccine vectors, as they correctly express transgenes in human cells, elicit complete immune responses, and show protective efficacy in preclinical animal models. At present, no information is available on the differences in the abortive replication of these two avipox viruses in mammalian cells. In the present study, the replicative cycles of CP and FP, wild… Expand
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