Canalization of the Vestibular Plate in the Absence of Urethral Fusion Characterizes Development of the Human Clitoris: The Single Zipper Hypothesis.

@article{Overland2016CanalizationOT,
  title={Canalization of the Vestibular Plate in the Absence of Urethral Fusion Characterizes Development of the Human Clitoris: The Single Zipper Hypothesis.},
  author={Maya Overland and Yi Li and Mei Zhen Cao and Joel Shen and Xuan Yue and Sisir Botta and Adriane Watkins Sinclair and Gerald R. Cunha and Laurence S. Baskin},
  journal={The Journal of urology},
  year={2016},
  volume={195 4 Pt 2},
  pages={1275-83}
}
PURPOSE We characterized the early gestation development of the female external genitalia using optical projection tomography to visualize anatomical structures at high resolution. MATERIALS AND METHODS First and early second trimester human female fetal external genitalia were collected with consent after voluntary termination. Specimens labeled with anti-E-Cadherin antibody underwent analysis with optical projection tomography. Histological sections were immunostained for androgen receptor… CONTINUE READING

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